Modulation of synaptic transmission and excitation-contraction coupling in the opener muscle of the crayfish, Astacus leptodactylus, by 5-hydroxytryptamine and octopamine.

@article{Fischer1983ModulationOS,
  title={Modulation of synaptic transmission and excitation-contraction coupling in the opener muscle of the crayfish, Astacus leptodactylus, by 5-hydroxytryptamine and octopamine.},
  author={L L Fischer and Ernst Florey},
  journal={The Journal of experimental biology},
  year={1983},
  volume={102},
  pages={187-98}
}
The modulatory actions of 5-hydroxytryptamine (5-HT) and octopamine (OA) were investigated in the opener nerve-muscle preparation of the crayfish, Astacus leptodactylus. Membrane resistance and resting potential were unaltered by 5-HT and OA at concentrations up to 2.5 X 10(-5) M; but EPSP-amplitudes were increased, up to 3-fold by OA and up to 18-fold by 5-HT. The lowest effective concentration was 2.5 X 10(-9) M; a maximal effect was produced at 2.5 X 10(-6) M. The effect was reversible only… CONTINUE READING

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Effects of catecholamines and cyclic AMP on excitation - contraction coupling in isolated skeletal muscle fibres of the frog

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Modulation of neuromuscular synaptic transmission by neurohormones . Experiments on the opener muscle of crayfish ( Astacus leptodactylus )

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