Modulation of single channels underlying hippocampal L-type current enhancement by agonists depends on the permeant ion.

@article{Tavalin2004ModulationOS,
  title={Modulation of single channels underlying hippocampal L-type current enhancement by agonists depends on the permeant ion.},
  author={Steven J. Tavalin and Dawn Shepherd and Robin K. Cloues and Sarah Bowden and Neil V. Marrion},
  journal={Journal of neurophysiology},
  year={2004},
  volume={92 2},
  pages={824-37}
}
The influx of calcium (Ca(2+)) ions through L-type channels underlies many cellular processes, ranging from initiation of gene transcription to activation of Ca(2+)-activated potassium channels. L-type channels possess a diagnostic pharmacology, being enhanced by the dihydropyridine BAY K 8644 and benzoylpyrrole FPL 64176. It is assumed that the action of… CONTINUE READING