Modulation of short-term plasticity in the corticothalamic circuit by group III metabotropic glutamate receptors.

@article{Kyuyoung2014ModulationOS,
  title={Modulation of short-term plasticity in the corticothalamic circuit by group III metabotropic glutamate receptors.},
  author={Christine L Kyuyoung and John R. Huguenard},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2014},
  volume={34 2},
  pages={675-87}
}
Recurrent connections in the corticothalamic circuit underlie oscillatory behavior in this network and range from normal sleep rhythms to the abnormal spike-wave discharges seen in absence epilepsy. The propensity of thalamic neurons to fire postinhibitory rebound bursts mediated by low-threshold calcium spikes renders the circuit vulnerable to both increased excitation and increased inhibition, such as excessive excitatory cortical drive to thalamic reticular (RT) neurons or heightened… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 87 references

Characterisation of an mGlu 8 receptorselective agonist and antagonist in the lateral and medial perforant path inputs to the dentate gyrus

  • RA Silver
  • Neuropharmacology
  • 2013

Characterisation of an mGlu8 receptor

  • GL, ZA Bortolotto
  • 2013

A new mode of corticothalamic transmission

  • JR Huguenard
  • 2011

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