Modulation of rat vaginal blood flow and estrogen receptor by estradiol.

@article{Kim2004ModulationOR,
  title={Modulation of rat vaginal blood flow and estrogen receptor by estradiol.},
  author={Soo Woong Kim and Noel N Kim and Seong-Joo Jeong and Ricardo M Munarriz and Irwin S. Goldstein and Abdulmaged M Traish},
  journal={The Journal of urology},
  year={2004},
  volume={172 4 Pt 1},
  pages={1538-43}
}
PURPOSE The effects of subphysiological and physiological levels of estradiol on vaginal blood flow and estrogen receptor were investigated. MATERIALS AND METHODS Intact or ovariectomized female Sprague-Dawley rats were used. Two weeks after surgery rats were infused with vehicle (polyethyleneglycol), or estradiol at subphysiological (5 microg daily) or physiological (15 microg daily) concentrations for 14 days using osmotic pumps. Changes in vaginal blood flow elicited by pelvic nerve… CONTINUE READING

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