Modulation of rabbit neutrophil aggregation and degranulation by free fatty acids.

Abstract

We have examined the effects of free fatty acids on the unstimulated and N-formyl-methionyl-leucyl-phenylalanine (f-Met-Leu-Phe) stimulated rabbit neutrophil aggregation and degranulation. As previously reported, arachidonic acid was found to induce by itself an aggregatory response, and in the presence of cytochalasin B, a degranulation response from the… (More)

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