Modulation of photo-oxidative DNA damage by cationic surfactant complexation.

Abstract

The natural packaging of DNA in the cell by histones provides a particular environment affecting its sensitivity to oxidative damage. In this work, we used the complexation of DNA by cationic surfactants to modulate the conformation, the dynamics, and the environment of the double helix. Photo-oxidative damage initiated by benzophenone as the… (More)
DOI: 10.1021/la800751k

Topics

9 Figures and Tables