Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase.

@article{Schmid2011ModulationOP,
  title={Modulation of pancreatic islets-stress axis by hypothalamic releasing hormones and 11beta-hydroxysteroid dehydrogenase.},
  author={Janine Schmid and Barbara M. Ludwig and Andrew V Schally and Anja Steffen and Christian G. Ziegler and Norman L . Block and Yassemi Koutmani and Mathias D. Brendel and Katia P. Karalis and Charmaine J Simeonovic and Julio Licinio and Monika Ehrhart-Bornstein and Stefan R. Bornstein},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2011},
  volume={108 33},
  pages={13722-7}
}
Corticotropin-releasing hormone (CRH) and growth hormone-releasing hormone (GHRH), primarily characterized as neuroregulators of the hypothalamic-pituitary-adrenal axis, directly influence tissue-specific receptor-systems for CRH and GHRH in the endocrine pancreas. Here, we demonstrate the expression of mRNA for CRH and CRH-receptor type 1 (CRHR1) and of… CONTINUE READING