Modulation of olfactory bulb neuron potassium current by tyrosine phosphorylation.

@article{Fadool1998ModulationOO,
  title={Modulation of olfactory bulb neuron potassium current by tyrosine phosphorylation.},
  author={Debra Ann Fadool and Irwin B. Levitan},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 16},
  pages={
          6126-37
        }
}
Insulin causes a suppression of whole-cell voltage-dependent outward current in cultured neurons from the rat olfactory bulb. This suppression is time-dependent; it is mimicked by application of Src tyrosine kinase inside the cell via the whole-cell patch electrode or by treatment of the olfactory bulb neurons with the tyrosine phosphatase inhibitor pervanadate. The C-type inactivation properties of the outward current in olfactory bulb neurons resemble those of the cloned Kv1.3 potassium… CONTINUE READING

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