Modulation of nitrergic relaxant responses by peptides in the mouse gastric fundus.

@article{Baccari2001ModulationON,
  title={Modulation of nitrergic relaxant responses by peptides in the mouse gastric fundus.},
  author={Maria Caterina Baccari and Franco Calamai},
  journal={Regulatory peptides},
  year={2001},
  volume={98 1-2},
  pages={27-32}
}
The effects of pituitary adenylate cyclase-activating peptide (PACAP-38) and vasoactive intestinal polypeptide (VIP) were investigated in the gastric fundus strips of the mouse. In carbachol (CCh) precontracted strips, in the presence of guanethidine, electrical field stimulation (EFS) elicited a fast inhibitory response that may be followed, at the highest stimulation frequencies employed, by a sustained relaxation. The fast response was abolished by the nitric oxide (NO) synthesis inhibitor L… CONTINUE READING
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