Modulation of neutrophil activity by submandibular gland peptide-T (SGP-T).


The heptapeptide submandibular gland peptide-T (SGP-T; sequence = Thr-Asp-Ile-Phe-Glu-Gly-Gly) was isolated from rat submandibular glands based on its ability to reduce endotoxic hypotension. Since these glands also modulate neutrophil function, the effects of SGP-T on neutrophil function were investigated. I.v. SGP-T (35 and 100 micrograms/kg), when… (More)


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