Modulation of myocardial alpha 1- but not beta-adrenoceptors after 90-day tail-suspension.

@article{Chen1996ModulationOM,
  title={Modulation of myocardial alpha 1- but not beta-adrenoceptors after 90-day tail-suspension.},
  author={Jianchu Chen and Li-fan Zhang and Chide Han and Georgy Yu and Jin Ma},
  journal={Journal of gravitational physiology : a journal of the International Society for Gravitational Physiology},
  year={1996},
  volume={3 1},
  pages={57-62}
}
We have previously demonstrated that prolonged simulated microgravity (tail-suspension) leads to cardiac alterations with increased resting heart rate, myocardial degradation changes and attenuated myocardial contractility. The present study investigated the potential role of adrenoceptor mechanisms underlying them. Changes of myocardial alpha 1-adrenoceptor (alpha 1-AR) and beta 1-adrenoceptor (beta-AR) in 90-day tail-suspended rats was investigated by the method of radioligand binding assay… CONTINUE READING

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