Modulation of mycobacterial-specific Th1 and Th17 cells in latent tuberculosis by coincident hookworm infection.

@article{George2013ModulationOM,
  title={Modulation of mycobacterial-specific Th1 and Th17 cells in latent tuberculosis by coincident hookworm infection.},
  author={Parakkal Jovvian George and Rajamanickam Anuradha and Paramasivam Paul Kumaran and Vedachalam Chandrasekaran and Thomas B Nutman and Subash Babu},
  journal={Journal of immunology},
  year={2013},
  volume={190 10},
  pages={5161-8}
}
Hookworm infections and tuberculosis (TB) are coendemic in many parts of the world. It has been suggested that infection with helminth parasites could suppress the predominant Th1 (IFN-γ-mediated) response needed to control Mycobacterium tuberculosis infection and enhance susceptibility to infection and/or disease. To determine the role of coincident hookworm infection on responses at steady-state and on M. tuberculosis-specific immune responses in latent TB (LTB), we examined the cellular… CONTINUE READING
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