Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic anti-DNA monoclonal antibody.

Abstract

Experimental systemic lupus erythematosus (SLE) can be induced in naive mice by immunization with a murine monoclonal anti-DNA antibody (mAb), 5G12, that bears a major idiotype designated 16/6 Id. Strain-dependent differences were observed in the proliferative responses of lymph node cells of mice immunized with two peptides based on the sequences of the… (More)

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Cite this paper

@article{Waisman1997ModulationOM, title={Modulation of murine systemic lupus erythematosus with peptides based on complementarity determining regions of a pathogenic anti-DNA monoclonal antibody.}, author={Ari Waisman and Pedro J. Garc{\'i}a Ruiz and Eli Israeli and Eran Eilat and Stephanie Koenen-Waisman and Heidey Zinger and M. Dayan and Emese M{\'o}zes}, journal={Proceedings of the National Academy of Sciences of the United States of America}, year={1997}, volume={94 9}, pages={4620-5} }