Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Calpha in C2C12 myocytes.

@article{Wang2006ModulationOM,
  title={Modulation of mitochondrial metabolic function by phorbol 12-myristate 13-acetate through increased mitochondrial translocation of protein kinase Calpha in C2C12 myocytes.},
  author={Ying Wang and Gopa Biswas and Subbuswamy K. Prabu and Narayan G Avadhani},
  journal={Biochemical pharmacology},
  year={2006},
  volume={72 7},
  pages={881-92}
}
Protein kinase C (PKC) agonists including phorbol 12-myristate 13-acetate (PMA) not only induce the redistribution of cytosolic PKC to various subcellular compartments but also activate the kinase domain of the protein. In the present study we have investigated the nature of mitochondrial PKC pool and its effects on mitochondrial function in cells treated… CONTINUE READING