Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson’s disease

@article{Liu2006ModulationOM,
  title={Modulation of microglial pro-inflammatory and neurotoxic activity for the treatment of Parkinson’s disease},
  author={Bin Liu},
  journal={The AAPS Journal},
  year={2006},
  volume={8},
  pages={E606-E621}
}
Parkinson’s disease (PD) is a debilitating movement disorder resulting from a progressive degeneration of the nigrostriatal dopaminergic pathway and depletion of neurotransmitter dopamine in the striatum. Molecular cloning studies have identified nearly a dozen genes or loci that are associated with small clusters of mostly early onset and genetic forms of PD. The etiology of the vast majority of PD cases remains unknown, and the precise molecular and biochemical processes governing the… CONTINUE READING

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In vivo imaging of microglial activation with [ 11 C ] ( R ) - PK 11195 PET in progressive supranuclear palsy

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