Modulation of membrane proteins by vertical phase separation and membrane lipid fluidity. Basis for a new approach to tumor immunotherapy.

@article{Muller1986ModulationOM,
  title={Modulation of membrane proteins by vertical phase separation and membrane lipid fluidity. Basis for a new approach to tumor immunotherapy.},
  author={Claude P. Muller and Gerhard R. F. Krueger},
  journal={Anticancer research},
  year={1986},
  volume={6 5},
  pages={
          1181-93
        }
}
Cell differentiation and proliferation entail a series of membranal events, which lead to the modulation of proteins at the cell surface. In the case of malignant differentiation this offers the tumor cell the possibility of escaping immune surveillance. Vertical phase separation of membrane proteins appears to play an important role during modulation of membrane proteins. The data reviewed here strongly suggests that the membrane lipid fluidity modulates expression of membrane proteins by… CONTINUE READING

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