Modulation of kinase activities in dauers and in long-lived mutants of Caenorhabditis elegans.

Abstract

Mutant alleles of the genes age-1 and daf-2 that lengthen life span (Age phenotype) of Caenorhabditis elegans cause higher protein kinase (PKA, PKC, PTK) activity levels in senescing worms relative to wild-type. Elevated levels of PKA and PTK were also present in dauer larvae, developmentally arrested juveniles specialized for long-term survival, relative… (More)

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@article{Vanfleteren1997ModulationOK, title={Modulation of kinase activities in dauers and in long-lived mutants of Caenorhabditis elegans.}, author={Jacques R. Vanfleteren and Annemie De Vreese}, journal={The journals of gerontology. Series A, Biological sciences and medical sciences}, year={1997}, volume={52 4}, pages={B212-6} }