Modulation of ionotropic GABA receptors by natural products of plant origin.

@article{Johnston2006ModulationOI,
  title={Modulation of ionotropic GABA receptors by natural products of plant origin.},
  author={G. Johnston and J. Hanrahan and M. Chebib and R. Duke and K. N. Mewett},
  journal={Advances in pharmacology},
  year={2006},
  volume={54},
  pages={
          285-316
        }
}
Publisher Summary This chapter discusses the modulation of ionotropic γ‐aminobutyric acid (GABA) receptors by natural products of plant origin. There is an impressive array of natural products that are known to influence the function of ionotropic receptors for GABA, the major inhibitory neurotransmitter in the brain. The major chemical classes of such natural products are flavonoids, terpenoids, phenols, and polyacetylenic alcohols. The interaction of flavonoids with benzodiazepine modulatory… Expand
Herbal Products and GABA Receptors
Efficient Modulation of γ-Aminobutyric Acid Type A Receptors by Piperine Derivatives
γ-Aminobutyric acid (GABA) signalling in plants
A Cycloartane Glycoside Derived from Actaea racemosa L. Modulates GABAA Receptors and Induces Pronounced Sedation in Mice
Esters of valerenic acid as potential prodrugs
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 164 REFERENCES
Novel Plant Substances Acting as β Subunit Isoform-Selective Positive Allosteric Modulators of GABAA Receptors
Flavonoids: some of the wisdom of sage?
Potentiation of the ionotropic GABA receptor response by whiskey fragrance.
GABA(A) receptor channel pharmacology.
  • G. Johnston
  • Biology, Medicine
  • Current pharmaceutical design
  • 2005
Structural requirements of phenol derivatives for direct activation of chloride currents via GABA(A) receptors.
Fragrances in Oolong Tea That Enhance the Response of GABAA Receptors
Interactions of flavones and other phytochemicals with adenosine receptors.
Overview—Flavonoids: A New Family of Benzodiazepine Receptor Ligands
...
1
2
3
4
5
...