Modulation of intestinal estrogen receptor by ovariectomy, estrogen and growth hormone.

@article{Chen1998ModulationOI,
  title={Modulation of intestinal estrogen receptor by ovariectomy, estrogen and growth hormone.},
  author={Chao-bo Chen and Dike N. Kalu},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={1998},
  volume={286 1},
  pages={328-33}
}
Ovarian hormone deficiency decreases and estrogen (E2) and growth hormone (GH) administrations increase intestinal absorption of calcium (Ca++). However, the underlying mechanisms are uncertain. To examine whether alterations in the binding characteristics of intestinal estrogen receptors (ERs) are involved, we developed and validated methods for simultaneous measurement of intestinal ERs in cytosolic and nuclear fractions and applied these techniques to four groups of female rats: sham… CONTINUE READING

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