Modulation of inflammation and disease tolerance by DNA damage response pathways.

@article{NevesCosta2017ModulationOI,
  title={Modulation of inflammation and disease tolerance by DNA damage response pathways.},
  author={Ana Neves-Costa and Luis Ferreira Moita},
  journal={The FEBS journal},
  year={2017},
  volume={284 5},
  pages={
          680-698
        }
}
The accurate replication and repair of DNA is central to organismal survival. This process is challenged by the many factors that can change genetic information such as replication errors and direct damage to the DNA molecule by chemical and physical agents. DNA damage can also result from microorganism invasion as an integral step of their life cycle or as collateral damage from host defense mechanisms against pathogens. Here we review the complex crosstalk of DNA damage response and immune… CONTINUE READING
4
Twitter Mentions

References

Publications referenced by this paper.
SHOWING 1-10 OF 103 REFERENCES

HMGB1-DNA complex-induced autophagy limits AIM2 inflammasome activation through RAGE.

  • Biochemical and biophysical research communications
  • 2014
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

The phosphoproteome of toll-like receptor-activated macrophages

  • Molecular systems biology
  • 2010
VIEW 17 EXCERPTS
HIGHLY INFLUENTIAL