Modulation of imprinted gene expression following superovulation.

  title={Modulation of imprinted gene expression following superovulation.},
  author={Amanda L Fortier and Serge McGraw and Flavia Lombardi Lopes and Kirsten M. Niles and Myl{\`e}ne Landry and Jacquetta M. Trasler},
  journal={Molecular and cellular endocrinology},
  volume={388 1-2},
Although assisted reproductive technologies increase the risk of low birth weight and genomic imprinting disorders, the precise underlying causes remain unclear. Using a mouse model, we previously showed that superovulation alters the expression of imprinted genes in the placenta at 9.5days (E9.5) of gestation. Here, we investigate whether effects of superovulation on genomic imprinting persisted at later stages of development and assess the surviving fetuses for growth and morphological… CONTINUE READING


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