Modulation of humoral immune response to oral BCG vaccination by Mycobacterium bovis BCG Moreau Rio de Janeiro (RDJ) in healthy adults

@article{MonteiroMaia2006ModulationOH,
  title={Modulation of humoral immune response to oral BCG vaccination by Mycobacterium bovis BCG Moreau Rio de Janeiro (RDJ) in healthy adults},
  author={Renata Monteiro-Maia and Maria B Ortig{\~a}o-de-Sampaio and Rosa Pinho and Luiz R R Castello-Branco},
  journal={Journal of Immune Based Therapies and Vaccines},
  year={2006},
  volume={4},
  pages={4 - 4}
}
BACKGROUND Oral administration of BCG was the route initially used by Calmette and Guérin, but was replaced by intradermal administration in virtually all countries after the Lubeck accident. However, Brazil continued to administer oral BCG Moreau RDJ, which was maintained until the mid-1970s when it was substituted by the intradermal route. Although BCG vaccination has been used in humans since 1921, little is known of the induced immune response. The aim of this study was to analyse… CONTINUE READING
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