Modulation of granulocyte LAM-1 and MAC-1 during dialysis--a prospective, randomized controlled trial.

@article{Himmelfarb1992ModulationOG,
  title={Modulation of granulocyte LAM-1 and MAC-1 during dialysis--a prospective, randomized controlled trial.},
  author={Jonathan Himmelfarb and P M Zaoui and Raymond M. Hakim},
  journal={Kidney international},
  year={1992},
  volume={41 2},
  pages={388-95}
}
Hemodialysis with first-use cellulosic dialysis membranes results in activation of the alternative pathway of complement and profound neutropenia followed by rebound leukocytosis. The neutropenia has been shown to be associated with increased expression of adhesion receptors and pulmonary sequestration of granulocytes. However, the mechanism underlying the return of the granulocytes has not been elucidated. We determined simultaneously the changes in the granulocyte adhesion receptor MAC-1… CONTINUE READING

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