Modulation of gonococcal piliation by regulatable transcription of pilE.

  title={Modulation of gonococcal piliation by regulatable transcription of pilE.},
  author={Cynthia D. Long and Stanley F. Hayes and Jos P M van Putten and Hillery A Harvey and Michael A. Apicella and H Steven Seifert},
  journal={Journal of bacteriology},
  volume={183 5},
The gonococcal pilus, a member of the type IV family of pili, is composed of numerous monomers of the pilin protein and plays an important role in the initiation of disease by providing the primary attachment of the bacterial cell to human mucosal tissues. Piliation also correlates with efficient DNA transformation. To investigate the relationships between these pilus-related functions, the piliation state, and the availability of pilin, we constructed a derivative of MS11-C9 (DeltapilE1) in… CONTINUE READING
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