Modulation of glutamate release from hippocampal mossy fiber nerve endings by arachidonic acid and eicosanoids.

@article{Dorman1992ModulationOG,
  title={Modulation of glutamate release from hippocampal mossy fiber nerve endings by arachidonic acid and eicosanoids.},
  author={Robert V. Dorman and T F Hamm and Derek S Damron and Ernest J. Freeman},
  journal={Advances in experimental medicine and biology},
  year={1992},
  volume={318},
  pages={121-36}
}
Arachidonic acid has been implicated in normal synaptic transmission processes, including those related to the development of hippocampal long-term synaptic potentiation. Hippocampal mossy fiber (MF) synaptosomes were used to investigate the role of arachidonate in the evoked accumulation of presynaptic Ca2+ and the release of endogenous glutamate, since… CONTINUE READING