Modulation of glutamate receptor functions by glutathione

  title={Modulation of glutamate receptor functions by glutathione},
  author={S. Oja and R. Jan{\'a}ky and V. Varga and P. Saransaari},
  journal={Neurochemistry International},
  • S. Oja, R. Janáky, +1 author P. Saransaari
  • Published 2000
  • Biology, Medicine
  • Neurochemistry International
  • In addition to its well-known antioxidant effects, glutathione apparently has an additional double role in the central nervous system as a neurotransmitter and neuromodulator. A number of recent neurochemical, neuropharmacological and electrophysiological studies have yielded evidence on both functions. As an excitatory neurotransmitter, glutathione depolarizes neurons by acting as ionotropic receptors of its own which are different from any other excitatory amino acid receptors. As a… CONTINUE READING
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