Modulation of gene expression via overlapping binding sites exerted by ZNF143, Notch1 and THAP11

@inproceedings{NgondoMbongo2013ModulationOG,
  title={Modulation of gene expression via overlapping binding sites exerted by ZNF143, Notch1 and THAP11},
  author={Richard Patryk Ngondo-Mbongo and Evelyne Myslinski and Jon C Aster and P. Carbon},
  booktitle={Nucleic acids research},
  year={2013}
}
ZNF143 is a zinc-finger protein involved in the transcriptional regulation of both coding and non-coding genes from polymerase II and III promoters. Our study deciphers the genome-wide regulatory role of ZNF143 in relation with the two previously unrelated transcription factors Notch1/ICN1 and thanatos-associated protein 11 (THAP11) in several human and murine cells. We show that two distinct motifs, SBS1 and SBS2, are associated to ZNF143-binding events in promoters of >3000 genes. Without co… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

ZNF143 is a regulator of chromatin loop

Cell Biology and Toxicology • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 50 references

Genomic study of RNA polymerase II and III SNAPc-bound promoters reveals a gene transcribed by both enzymes and a broad use of common activators

N. James Faresse, D. Canella, +3 authors N. Hernandez
PLoS Genet., • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…