Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta.

@article{Babalola1995ModulationOG,
  title={Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta.},
  author={G O Babalola and Richard M Schultz},
  journal={Molecular reproduction and development},
  year={1995},
  volume={41 2},
  pages={133-9}
}
The effect of growth factors on regulating gene expression in the preimplantation mouse embryo was examined, since results of previous experiments revealed a stimulatory effect of exogenously-added growth factors on preimplantation development in vitro. Treatment of early cavitating blastocysts with either 250 pM TGF-alpha or TGF-beta results in changes in the pattern of total protein synthesis as assessed by high-resolution two-dimensional gel electrophoresis. In some cases, the synthesis of a… CONTINUE READING
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