Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta.

@article{Dub2012ModulationOF,
  title={Modulation of fatty acid transport and metabolism by maternal obesity in the human full-term placenta.},
  author={Evemie Dub{\'e} and Ariane Gravel and Coralie Martin and Guillaume Desparois and Issa Moussa and Maude {\'E}thier-Chiasson and Joelle Forest and Yves Gigu{\`e}re and Andr{\'e} Masse and Jean-luc Lafond},
  journal={Biology of reproduction},
  year={2012},
  volume={87 1},
  pages={
          14, 1-11
        }
}
Knowledge of the consequences of maternal obesity in human placental fatty acids (FA) transport and metabolism is limited. Animal studies suggest that placental uptake of maternal FA is altered by maternal overnutrition. We hypothesized that high maternal body mass index (BMI) affects human placental FA transport by modifying expression of key transporters. Full-term placentas were obtained by vaginal delivery from normal weight (BMI, 18.5-24.9 kg/m(2)) and obese (BMI > 30 kg/m(2)) women. Blood… CONTINUE READING
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