Modulation of extracellular matrix turnover in the trabecular meshwork.

@article{Fuchshofer2009ModulationOE,
  title={Modulation of extracellular matrix turnover in the trabecular meshwork.},
  author={Rudolf Fuchshofer and Ernst R Tamm},
  journal={Experimental eye research},
  year={2009},
  volume={88 4},
  pages={683-8}
}
Intraocular pressure (IOP) is the most critical risk factor for primary open angle glaucoma (POAG). In most cases of POAG, IOP is increased because of an abnormally high aqueous humor outflow resistance in the juxtacanalicular region of the trabecular meshwork. A distinct structural change in the trabecular meshwork of patients with POAG is the increase in fibrillar extracellular matrix in the juxtacanalicular region of the trabecular meshwork. Our knowledge on the molecular factors that govern… CONTINUE READING

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