Modulation of efflux proteins by electromagnetic field for delivering azidothymidine and saquinavir into the brain.

Abstract

An exposure to an electromagnetic field (EMF) has been shown to enhance the membrane permeability of endothelial cells. This study investigates the effect of EMF on the modulation of P-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) for delivering saquinavir (SQV) and azidothymidine (AZT). To assess the transport of SQV and AZT, an EMF… (More)
DOI: 10.1016/j.colsurfb.2011.11.020

Topics

Cite this paper

@article{Kuo2012ModulationOE, title={Modulation of efflux proteins by electromagnetic field for delivering azidothymidine and saquinavir into the brain.}, author={Yung-Chih Kuo and Chin-Hsun Lu}, journal={Colloids and surfaces. B, Biointerfaces}, year={2012}, volume={91}, pages={291-5} }