Modulation of early growth response gene 1 and interleukin-8 expression by ribotoxin deoxynivalenol (vomitoxin) via ERK1/2 in human epithelial intestine 407 cells.

@article{Moon2007ModulationOE,
  title={Modulation of early growth response gene 1 and interleukin-8 expression by ribotoxin deoxynivalenol (vomitoxin) via ERK1/2 in human epithelial intestine 407 cells.},
  author={Y. B. Moon and Hyun Ho Yang and Soo Hyung Lee},
  journal={Biochemical and biophysical research communications},
  year={2007},
  volume={362 2},
  pages={256-62}
}
Epithelium senses external toxic insults transmit the sentinel signals into the cells to reprogram a broad range of mucosal responses like epithelial inflammatory diseases. The purpose of this study was to test the hypothesis that ribotoxin DON evokes the epithelial sentinel signals which contributes to the pro-inflammatory cytokine interleukin-8 in human… CONTINUE READING