Modulation of drug release from hydrophilic matrices Literature searches indicate that a wide array of natural and synthetic polymers have been utilized as hydrophilic matrices in monolithic dosage forms


A hydrophilic matrix tablet is the simplest and most cost-effective method of fabricating an extended release (ER) solid oral dosage form. The majority of commercially available matrix formulations are in the form of tablets, and their method of manufacture is similar to conventional tablet formulations: granulation, blending, compression and coating. In… (More)


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