Modulation of dopamine release by striatal 5-HT2C receptors.

  title={Modulation of dopamine release by striatal 5-HT2C receptors.},
  author={Katherine D Alex and Gregory J. Yavanian and Hewlet G McFarlane and Charles P. Pluto and Elizabeth A. Pehek},
  volume={55 4},
Previous work has demonstrated that dopamine (DA) transmission is regulated by serotonin-2C (5-HT2C) receptors but the site(s) in the brain where these receptors are localized is not known. The present work utilized in vivo microdialysis to investigate the modulation of DA release by 5-HT2C receptors localized in the nerve terminal regions of the mesocortical and nigrostriatal DA pathways. Microdialysis probes implanted in the striatum or the prefrontal cortex (PFC) measured dialysate DA… CONTINUE READING
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