Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins.

@article{Uustare2006ModulationOD,
  title={Modulation of dopamine D1 receptor signaling by adenosine A1 receptors in Sf9 cells requires expression of Gi proteins.},
  author={Ain Uustare and Reet Reinart and Ago Rinken},
  journal={Neuroscience letters},
  year={2006},
  volume={406 3},
  pages={169-73}
}
There are several evidences that some functions of D1 dopamine receptors can be modulated by colocalized adenosine A1 receptors. To elucidate the role of particular components of the receptor complex in the ligand binding and second messenger activation level we have used Sf9 cell expression system. The expression of D1 and A1 receptors was confirmed by… CONTINUE READING