Modulation of diamide toxicity in thermotolerant cells by inhibition of protein synthesis.

@article{Freeman1989ModulationOD,
  title={Modulation of diamide toxicity in thermotolerant cells by inhibition of protein synthesis.},
  author={Michael L Freeman and Michael J. Meredith},
  journal={Cancer research},
  year={1989},
  volume={49 16},
  pages={4493-8}
}
Chinese hamster ovary cells were exposed in vitro to various concentrations of diamide for 1 h at 37 degrees C. This treatment resulted in a dose dependent increase in cytotoxicity. Cells were also heated at 43 degrees C for 15 min, incubated at 37 degrees C for 3 h, and then exposed to various concentrations of diamide. This heat shock has been shown… CONTINUE READING