Modulation of dendritic cells and toll-like receptors by marathon running

  title={Modulation of dendritic cells and toll-like receptors by marathon running},
  author={Thomas Nickel and Ingrid Emslander and Zeljka Sisic and R. David and Christoph Schmaderer and Niko Marx and Arno Schmidt-Trucks{\"a}ss and Eva Hoster and Martin Halle and Michael Weis and Henner Hanssen},
  journal={European Journal of Applied Physiology},
The focus of this study was to assess exercise-induced alterations of circulating dendritic cell (DC) subpopulations and toll-like receptor (TLR) expression after marathon running. Blood sampling was performed in 15 obese non-elite (ONE), 16 lean non-elite (LNE) and 16 lean elite (LE) marathon runners pre- and post-marathon as well as 24 h after the race. Circulating DC-fractions were measured by flow-cytometry analyzing myeloid DCs (BDCA-1+) and plasmacytoid DCs (BDCA-2+). We further analyzed… CONTINUE READING