Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor

@article{Carobrez2001ModulationOD,
  title={Modulation of defensive behavior by periaqueductal gray NMDA/glycine-B receptor},
  author={Antonio P. Carobrez and Karina Valerim Teixeira and Frederico Guilherme Graeff},
  journal={Neuroscience \& Biobehavioral Reviews},
  year={2001},
  volume={25},
  pages={697-709}
}
Role of glutamate NMDA receptors and nitric oxide located within the periaqueductal gray on defensive behaviors in mice confronted by predator
TLDR
Findings suggest a potential role of glutamate NMDA receptors and NO in the dPAG in the regulation of defensive behaviors in mice during a confrontation with a predator in the rat exposure test (RET).
Involvement of dorsolateral periaqueductal gray N-methyl-D-aspartic acid glutamate receptors in the regulation of risk assessment and inhibitory avoidance behaviors in the rat elevated T-maze
TLDR
The present results suggest that the dorsolateral periaqueductal gray column is also involved in the regulation of defensive behaviors related to anxiety, and N-methyl-D-aspartic acid glutamate receptors are recruited for this action.
Anxiolytic-like effects of NMDA/glycine-B receptor ligands are abolished during the elevated plus-maze trial 2 in rats
TLDR
The present findings favor the hypothesis in which the OTT phenomenon emerge as a consequence of the development and adoption of an anxiolytic-insensitive behavioral strategy, and emphasize the repeated test exposure rather than repeated drug administration as a critical determinant for the drug anxIOlytic activity.
The dorsolateral periaqueductal grey N-methyl-D-aspartate/nitric oxide/cyclic guanosine monophosphate pathway modulates the expression of contextual fear conditioning in rats
TLDR
Findings suggest that activity of dlPAG NMDA/NO/cyclic guanosine monophosphate (cGMP) pathway facilitates the expression of contextual fear responses.
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