Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant

@article{Venkatesan1995ModulationOC,
  title={Modulation of cyclophosphamide-induced early lung injury by curcumin, an anti-inflammatory antioxidant},
  author={N. E. Venkatesan and Gowri Chandrakasan},
  journal={Molecular and Cellular Biochemistry},
  year={1995},
  volume={142},
  pages={79-87}
}
Cyclophosphamide causes lung injury in rats through its ability to generate free radicals with subsequent endothelial and epithelial cell damage. In order to observe the protective effects of a potent anti-inflammatory antioxidant, curcumin (diferuloyl methane) on cyclophosphamide-induced early lung injury, healthy pathogen free male Wistar rats were exposed to 20 mg/100 g body weight of cyclophosphamide, intraperitoneally as a single injection. Prior to cyclophosphamide intoxication oral… CONTINUE READING
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