Modulation of corneal epithelial stratification by polymer surface topography.

  title={Modulation of corneal epithelial stratification by polymer surface topography.},
  author={Beatrice A Dalton and Margaret D. M. Evans and Gail A McFarland and John G. Steele},
  journal={Journal of biomedical materials research},
  volume={45 4},
The topography and porosity of a polymer may affect the epithelialization of a corneal implant. We used an in vitro model to examine the effect of polymer surface topography on corneal epithelial tissue stratification and the deposition of proteins associated with epithelial adhesion. A range of topographies was provided by polycarbonate membranes with nominal pore diameters of 0.1, 0.4, 0.8, 1.0, 2.0, or 3.0 microm and a nonporous surface. Stratification of epithelial tissue outgrowth on these… CONTINUE READING

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