Modulation of clonogenicity, growth, and radiosensitivity of three human epidermoid tumor cell lines by a fibroblastic environment.

@article{Gery1996ModulationOC,
  title={Modulation of clonogenicity, growth, and radiosensitivity of three human epidermoid tumor cell lines by a fibroblastic environment.},
  author={B Gery and Jacques Coppey and J. B. Little},
  journal={International journal of radiation oncology, biology, physics},
  year={1996},
  volume={34 5},
  pages={1061-71}
}
PURPOSE To develop a model vitro system to examine the influence of fibroblasts on the growth and survival of human tumor cells after exposure to ionizing radiation. METHODS AND MATERIALS The cell system of three epidermoid carcinoma cell lines derived from head and neck tumors having differing growth potentials and intrinsic radiosensitivities, as well as a low passage skin fibroblast strain from a normal human donor. The tumor cells were seeded for five days prior to exposure to radiation… CONTINUE READING