Modulation of cerebral catecholamine concentrations during hyperphenylalaninaemia.


Hyperphenylalaninaemia induced by daily injections of alpha-methylphenylalanine plus phenylalanine caused 20-40% decreases in cerebral dopamine (3,4-dihydroxyphenethylamine) and noradrenaline in 7- and 11-day-old rats. alpha-Methylphenylalanine alone as well as phenylalanine alone caused cerebral dopamine depletion. However, the effects were not additive… (More)


Cite this paper

@article{Brass1982ModulationOC, title={Modulation of cerebral catecholamine concentrations during hyperphenylalaninaemia.}, author={Clifford A. Brass and Olga Greengard}, journal={The Biochemical journal}, year={1982}, volume={208 3}, pages={765-71} }