Modulation of central nervous system-specific microRNA-124a alters the inflammatory response in the formalin test in mice.

@article{Kynast2013ModulationOC,
  title={Modulation of central nervous system-specific microRNA-124a alters the inflammatory response in the formalin test in mice.},
  author={Katharina L. Kynast and Otto Quintus Russe and Christine V. M{\"o}ser and Gerd 7 Geisslinger and Ellen Niederberger},
  journal={Pain},
  year={2013},
  volume={154 3},
  pages={368-76}
}
microRNAs (miRNAs) are small noncoding RNAs that have been linked to a number of disease-related signal transduction pathways. Several studies indicate that they are also involved in nociception. It is not clear, however, which miRNAs are important and which genes are modulated by miRNA-associated mechanisms. This study focuses on the regulation and function of the central nervous system (CNS)-specific miRNA-124a in the spinal cord of mice in a formalin model of inflammatory nociception. miRNA… CONTINUE READING
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