Modulation of cardiac fibrosis by Krüppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes.

Abstract

AIMS Krüppel-like factors (KLFs) are a family of transcription factors which play important roles in the heart under pathological and developmental conditions. We previously identified and cloned Klf6 whose homozygous mutation in mice results in embryonic lethality suggesting a role in cardiovascular development. Effects of KLF6 on pathological regulation… (More)
DOI: 10.1093/cvr/cvv155

Cite this paper

@article{Sawaki2015ModulationOC, title={Modulation of cardiac fibrosis by Kr{\"{u}ppel-like factor 6 through transcriptional control of thrombospondin 4 in cardiomyocytes.}, author={Daigo Sawaki and Lianguo Hou and Shota Tomida and Junqing Sun and Hong Zhan and Kenichi Aizawa and Bo-Kyung Son and Taro Kariya and Eiki Takimoto and Kinya Otsu and Simon J. Conway and Ichiro Manabe and Issei Komuro and Scott L Friedman and Ryozo Nagai and Toru Suzuki}, journal={Cardiovascular research}, year={2015}, volume={107 4}, pages={420-30} }