Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome.

Abstract

Heart disease remains the leading cause of death and disability in the Western world. Current therapies aim at treating the symptoms rather than the subcellular mechanisms, underlying the etiology and pathological remodeling in heart failure. A universal characteristic, contributing to the decreased contractile performance in human and experimental failing… (More)
DOI: 10.1161/CIRCRESAHA.111.259754

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@article{Kranias2012ModulationOC, title={Modulation of cardiac contractility by the phospholamban/SERCA2a regulatome.}, author={Evangelia G. Kranias and Roger J. Hajjar}, journal={Circulation research}, year={2012}, volume={110 12}, pages={1646-60} }