Modulation of calcium-activated non-selective cation channel activity by nitric oxide in rat brown adipose tissue.

@article{Koivisto1995ModulationOC,
  title={Modulation of calcium-activated non-selective cation channel activity by nitric oxide in rat brown adipose tissue.},
  author={Ari Koivisto and Jan Nedergaard},
  journal={The Journal of physiology},
  year={1995},
  volume={486 ( Pt 1)},
  pages={59-65}
}
1. Single-channel calcium-activated non-selective cation currents from isolated rat brown fat cells were measured using the inside-out patch configuration of the patch-clamp technique. The existence of a possible modulatory effect of nitric oxide on the putative redox-modulatory site located on the intracellular side of the non-selective cation channel was investigated. 2. The nitric oxide-releasing substances nitroglycerin, sodium nitroprusside, S-nitrosocysteine and S-nitroso-N-acetyl-D,L… CONTINUE READING

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