Modulation of bronchial epithelial cell barrier function by in vitro jet propulsion fuel 8 exposure.

  title={Modulation of bronchial epithelial cell barrier function by in vitro jet propulsion fuel 8 exposure.},
  author={Raymond F. Robledo and David S. Barber and M. Witten},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  volume={51 1},
The loss of epithelial barrier integrity in bronchial and bronchiolar airways may be an initiating factor in the observed onset of toxicant-induced lung injuries. Acute 1-h inhalation exposures to aerosolized jet propulsion fuel 8 (JP-8) have been shown to induce cellular and morphological indications of pulmonary toxicity that was associated with increased respiratory permeability to 99mTc-DTPA. To address the hypothesis that JP-8 jet fuel-induced lung injury is initiated through a disruption… CONTINUE READING
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