Modulation of brain progestin and glucocorticoid receptors by unsaturated fatty acid and phospholipid.

@article{Kato1987ModulationOB,
  title={Modulation of brain progestin and glucocorticoid receptors by unsaturated fatty acid and phospholipid.},
  author={Junzo Kato and Atsuko Takano and Naomi Mitsuhashi and Nobuyuki Koike and Koji Yoshida and Shizuko Hirata},
  journal={Journal of steroid biochemistry},
  year={1987},
  volume={27 4-6},
  pages={641-8}
}
In an attempt to learn how nonsteroidal factors modulate brain progestin and glucocorticoid receptors, the effects of saturated and unsaturated fatty acids, and phosphatidylinositol on the binding of [3H]R5020 or [3H]dexamethasone, determined by sucrose density gradient and gel filtration on LH20, were examined in the cerebral cortical cytosol from 10-day-old female rats which contain a considerable amount of progestin and glucocorticoid receptors. Unsaturated fatty acids such as oleic (C18:1… CONTINUE READING

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