Corpus ID: 24019597

Modulation of biomarkers by chemopreventive agents in smoke-exposed rats.

@article{Izzotti2001ModulationOB,
  title={Modulation of biomarkers by chemopreventive agents in smoke-exposed rats.},
  author={A. Izzotti and R. Balansky and F. Dagostini and C. Bennicelli and S. Myers and C. Grubbs and R. Lubet and G. Kelloff and S. De Flora},
  journal={Cancer research},
  year={2001},
  volume={61 6},
  pages={
          2472-9
        }
}
Chemoprevention opens new perspectives in the prevention of cancer and other chronic degenerative diseases associated with tobacco smoking, exploitable in current smokers and, even more, in exsmokers and passive smokers. Evaluation of biomarkers in animal models is an essential step for the preclinical assessment of efficacy and safety of potential chemopreventive agents. Groups of Sprague Dawley rats were exposed whole body to a mixture of mainstream and sidestream cigarette smoke for 28… Expand
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