Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.

@article{Bockor2017ModulationOB,
  title={Modulation of bilirubin neurotoxicity by the Abcb1 transporter in the Ugt1-/- lethal mouse model of neonatal hyperbilirubinemia.},
  author={Luka Bockor and Giulia Bortolussi and Simone Vodret and Alessandra Iaconcig and Jana Ja{\vs}prov{\'a} and Jaroslav Zelenka and Libor V{\'i}tek and Claudio Tiribelli and Andr{\'e}s F Muro},
  journal={Human molecular genetics},
  year={2017},
  volume={26 1},
  pages={145-157}
}
Moderate neonatal jaundice is the most common clinical condition during newborn life. However, a combination of factors may result in acute hyperbilirubinemia, placing infants at risk of developing bilirubin encephalopathy and death by kernicterus. While most risk factors are known, the mechanisms acting to reduce susceptibility to bilirubin neurotoxicity… CONTINUE READING